Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)-

Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)- - Names and Identifiers

Name	2,5-Bis(trifluoromethyl)benzenesulphonyl chloride
Synonyms	2,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 2,5-bis(trifluoroMethyl)benzene-1-sulfonyl chlori 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride 2,5-BIS(TRIFLUOROMETHYL)BENZENESULPHONYL CHLORIDE TRANS-(1R,2R)-N,N''-DIMETHYL-1,2-CYCLOHEXANEDIAMINE 2,5-bis(trifluoroMethyl)benzene-1-sulfonyl chloride Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)-
CAS	351003-22-0
EINECS	624-444-5
InChI	InChI=1/C7H5ClF2O3S/c8-14(11,12)6-3-1-5(2-4-6)13-7(9)10/h1-4,7H

Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C8H3ClF6O2S
Molar Mass	312.62
Density	1.618±0.06 g/cm3(Predicted)
Melting Point	59-63 °C (lit.)
Boling Point	277.6±40.0 °C(Predicted)
Flash Point	141.3°C
Vapor Presure	0.00112mmHg at 25°C
Storage Condition	Room Temprature
Sensitive	Hygroscopic
Refractive Index	1.494
MDL	MFCD03094042

Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)- - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3261 8/PG 2
WGK Germany	3
Hazard Note	Corrosive/Hygroscopic
Hazard Class	8
Packing Group	III

Benzenesulfonyl chloride, 2,5-bis(trifluoromethyl)- - Introduction

2,5-Bis(trifluoromethyl)benzenesulphonyl chloride is an organic compound with the chemical formula C8H3ClF6O2S. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride is a colorless or light yellow liquid.
-Melting point: about -18 ℃.
-Boiling point: about 130-135 ℃.
-Density: about 1.6g/cm³.
-Relative molecular mass: about 344.15g/mol.

Use:
- 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride can be used in organic synthesis as an important reagent.
-It is often used as an intermediate for the preparation of organic compounds such as drugs, dyes and pesticides.

Preparation Method:
- 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride can be prepared by chlorination of 2,5-bis (trifluoromethyl) benzenesulfonamide.
-Chlorination reactions typically use an electrophilic chlorine source, such as thionyl chloride (SO2Cl2).

Safety Information:
- 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride is irritating and care should be taken to avoid contact with skin and eyes. Wear appropriate protective equipment such as chemical protective gloves, protective goggles and face shields during operation.
-During storage and handling, the compound should be kept in a dry, well-ventilated place, away from ignition and oxidizing agents.
- 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride has certain stability in water, but it will hydrolyze to generate the corresponding acid and sulfonyl chloride when encountering alkaline substances.

Please note that this information is for reference only. The specific use and operation need to be based on the actual situation and comply with relevant safety operation procedures.

Last Update：2024-04-09 15:17:56